Statins as potent antiinflammatory drugs

被引：159

作者：

Lefer, DJ ^{[1
]}

机构：

[1] Louisiana State Univ, Hlth Sci Ctr, Dept Cellular & Mol Physiol, Shreveport, LA 71130 USA

来源：

CIRCULATION | 2002年 / 106卷 / 16期

关键词：

editorials; statins; nitric oxide synthase; leukocytes;

D O I：

10.1161/01.CIR.0000033635.42612.88

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2041 / 2042

页数：2

共 20 条

[1] Early and sustained survival benefit associated with statin therapy at the time of percutaneous coronary intervention [J].

Chan, AW ;

Bhatt, DL ;

Chew, DP ;

Quinn, MJ ;

Moliterno, DJ ;

Topol, EJ ;

Ellis, SG .

CIRCULATION, 2002, 105 (06) :691-696

[2] Association between enhanced soluble CD40L and prothrombotic state in hypercholesterolemia effects of statin therapy [J].

Cipollone, F ;

Mezzetti, A ;

Porreca, E ;

Di Febbo, C ;

Nutini, M ;

Fazia, M ;

Falco, A ;

Cuccurullo, F ;

Davì, G .

CIRCULATION, 2002, 106 (04) :399-402

[3] Withdrawal of statins increases event rates in patients with acute coronary syndromes [J].

Heeschen, C ;

Hamm, CW ;

Laufs, U ;

Snapinn, S ;

Böhm, M ;

White, HD .

CIRCULATION, 2002, 105 (12) :1446-1452

[4] Pretreatment with simvastatin attenuates myocardial dysfunction after ischemia and chronic reperfusion [J].

Jones, SP ;

Trocha, SD ;

Lefer, DJ .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2001, 21 (12) :2059-2064

[5] The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. [J].

Kureishi, Y ;

Luo, ZY ;

Shiojima, I ;

Bialik, A ;

Fulton, D ;

Lefer, DJ ;

Sessa, WC ;

Walsh, K .

NATURE MEDICINE, 2000, 6 (09) :1004-1010

[6] Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by rho GTPase [J].

Laufs, U ;

Liao, JK .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (37) :24266-24271

[7] Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase [J].

Laufs, U ;

LaFata, V ;

Liao, JK .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (50) :31725-31729

[8] Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors [J].

Laufs, U ;

La Fata, V ;

Plutzky, J ;

Liao, JK .

CIRCULATION, 1998, 97 (12) :1129-1135

[9] Vascular effects of HMG CoA-reductase inhibitors (statins) unrelated to cholesterol lowering: new concepts for cardiovascular disease [J].

Lefer, AM ;

Scalia, R ;

Lefer, DJ .

CARDIOVASCULAR RESEARCH, 2001, 49 (02) :281-287

[10] Simvastatin preserves the ischemic-reperfused myocardium in normocholesterolemic rat hearts [J].

Lefer, AM ;

Campbell, B ;

Shin, YK ;

Scalia, R ;

Hayward, R ;

Lefer, DJ .

CIRCULATION, 1999, 100 (02) :178-184

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