Invasive Haemophilus influenzae type b (Hib) infection in an adult patient with a selective deficiency of antibody to the Hib capsular polysaccharide

被引：8

作者：

Follin, P ^{[1
]}

Ulanova, M ^{[1
]}

HahnZoric, M ^{[1
]}

Hanson, LA ^{[1
]}

机构：

[1] GOTHENBURG UNIV,DEPT CLIN IMMUNOL,GOTHENBURG,SWEDEN

来源：

CLINICAL INFECTIOUS DISEASES | 1997年 / 25卷 / 04期

关键词：

D O I：

10.1086/515538

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A 31-year-old woman without any underlying disease contracted severe invasive Haemophilus influenzae type b (Hib) infection but developed no antibodies to the Hib capsular polysaccharide. Serum immunoglobulin levels were normal, but she had an isolated deficiency of antibody to Hib. Subsequently, immunization with a tetanus toxoid-conjugated Hib vaccine induced only a minimal response. However, she had a protective level of antibody (>1 mu g/mL) after the fifth vaccination.

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页码：915 / 917

页数：3

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