Failure to detect binding of LcrH to the V antigen of Yersinia pestis

被引：11

作者：

Fields, KA ^{[1
]}

Williams, AW ^{[1
]}

Straley, SC ^{[1
]}

机构：

[1] UNIV KENTUCKY,ALBERT B CHANDLER MED CTR,DEPT MICROBIOL & IMMUNOL,LEXINGTON,KY 40536

来源：

INFECTION AND IMMUNITY | 1997年 / 65卷 / 09期

关键词：

D O I：

10.1128/IAI.65.9.3954-3957.1997

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

V antigen of Yersinia pestis has been reported to bind the chaperone LcrH. We were unable to demonstrate this interaction. Despite methodological differences between our study and an earlier study, we believe that the previous findings were artifactual. One likely confounding element was the tendency of LcrH to adhere on its own to metal chelation chromatographic resin.

引用

页码：3954 / 3957

页数：4

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