Cancer Treatment-Related Neuropathic Pain Syndromes-Epidemiology and Treatment: An Update

被引：30

作者：

Smith, Ellen M. Lavoie ^{[1
]}

Bridges, Celia M. ^{[1
]}

Kanzawa, Grace ^{[1
]}

Knoerl, Robert ^{[1
]}

Kelly, James P. ^{[2
]}

Berezovsky, Anna ^{[2
]}

Woo, Charis ^{[1
]}

机构：

[1] Univ Michigan, Sch Nursing, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Ann Arbor, MI 48109 USA

来源：

CURRENT PAIN AND HEADACHE REPORTS | 2014年 / 18卷 / 11期

关键词：

Neuropathic pain; Chronic pain; Cancer treatment-related pain; INDUCED PERIPHERAL NEUROPATHY; POSTTRAUMATIC-STRESS-DISORDER; PARTIAL BREAST IRRADIATION; INTIMATE PARTNER VIOLENCE; CHRONIC POSTSURGICAL PAIN; PLACEBO-CONTROLLED TRIAL; QUALITY-OF-LIFE; TERM-FOLLOW-UP; RISK-FACTORS; PHARMACOLOGICAL MANAGEMENT;

D O I：

10.1007/s11916-014-0459-7

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

100204 [神经病学];

摘要：

Cancer treatment-related chronic neuropathic pain (NP) is a pervasive and distressing problem that negatively influences function and quality of life for countless cancer survivors. It occurs because of cancer treatment-induced damage to peripheral and central nervous system structures. NP becomes chronic when pain signal transmission persists, eventually sensitizing neurons in the dorsal horn and other pain-processing regions in the central nervous system. Frequently overlooked, NP due to cancer treatment has been understudied. Consequently, only a few pharmacologic interventions have been shown to be effective based on the results of randomized controlled trials. Future research designed to explore pathophysiologic mechanisms and effective mechanism-targeted interventions is sorely needed.

引用

页码：1 / 10

页数：10

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