Squamous cell carcinoma arising in a psoriatic nail bed: case report with discussion of diagnostic difficulties and therapeutic options

被引：13

作者：

Dobson, CM

Azurdia, RM

King, CM

机构：

[1] Royal Liverpool Univ Hosp, Dept Dermatol, Liverpool L7 8XP, Merseyside, England

[2] Royal Liverpool Univ Hosp, Dept Pathol, Liverpool L7 8XP, Merseyside, England

来源：

BRITISH JOURNAL OF DERMATOLOGY | 2002年 / 147卷 / 01期

关键词：

psoriatic nail bed; squamous cell carcinoma; verrucous carcinoma;

D O I：

10.1046/j.1365-2133.2002.04725.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We describe a squamous cell carcinoma arising from a psoriatic nail bed. The tumour had a verrucous surface and was very well differentiated, raising the possibility of early verrucous carcinoma. Occurrence of any type of squamous carcinoma in this site and background is extremely rare. Particular diagnostic and therapeutic questions arise in this unusual setting. We discuss the aetiology and diagnostic differentiation from other nail bed squamoproliferative lesions, particularly so-called subungual keratoacanthoma. We also discuss therapeutic options, including Moh's surgery and retinoids.

引用

页码：144 / 149

页数：6

共 36 条

[1] KERATOACANTHOMA VERSUS SQUAMOUS-CELL CARCINOMA - AN IMMUNOHISTOCHEMICAL REAPPRAISAL OF P53 PROTEIN AND PROLIFERATING CELL NUCLEAR ANTIGEN EXPRESSION IN KERATOACANTHOMA-LIKE TUMORS [J].