Cognitive effects of repetitive transcranial magnetic stimulation in patients with neurodegenerative diseases - Clinician's perspective

被引：76

作者：

Anderkova, Lubomira

Rektorova, Irena

机构：

[1] Masaryk Univ, Dept Neurol 1, Sch Med, Brno, Czech Republic

[2] St Annes Teaching Hosp, Brno, Czech Republic

[3] Masaryk Univ, CEITEC MU, Cent European Inst Technol, Appl Neurosci Res Grp, Brno, Czech Republic

来源：

JOURNAL OF THE NEUROLOGICAL SCIENCES | 2014年 / 339卷 / 1-2期

关键词：

rTMS; Cognition; Alzheimer's disease; Parkinson's disease; MCI; Neurodegenerative; Systematic review; DORSOLATERAL PREFRONTAL CORTEX; NONINVASIVE BRAIN-STIMULATION; NEUROLOGICAL MANAGEMENT GUIDELINES; TREATMENT-RESISTANT DEPRESSION; OBSESSIVE-COMPULSIVE DISORDER; SCIENTIFIC TASK-FORCES; HIGH-FREQUENCY RTMS; PARKINSONS-DISEASE; DOUBLE-BLIND; ALZHEIMERS-DISEASE;

D O I：

10.1016/j.jns.2014.01.037

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

100204 [神经病学];

摘要：

Repetitive transcranial magnetic stimulation (rTMS) represents a promising tool for studying and influencing cognition in people with neurodegenerative diseases. This procedure is noninvasive and painless, and it does not require the use of anesthesia or pharmacological substances. In this systematic critical review we report outcomes from research focused on behavioral cognitive effects induced by rTMS in patients with Alzheimer's disease (AD), Parkinson's disease (PD), and mild cognitive impairment (MCI) preceding AD. There are still major limitations to rTMS use, such as a poor understanding of its after-effects and inter-individual variability in their magnitude, discrepancies in stimulation protocols and study designs, varied selection of the specific stimulated areas and control procedures, and neuropsychological methods for assessment of after-effects; hence, the results of the present research can only be considered preliminary. The future directions are discussed. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：15 / 25

页数：11

共 104 条

[1]

Comparison of "standard" and "navigated" procedures of TMS coil positioning over motor, premotor and prefrontal targets in patients with chronic pain and depression [J].