Bacterial cell division: assembly, maintenance and disassembly of the Z ring

被引：633

作者：

Adams, David W. ^{[1
]}

Errington, Jeff ^{[1
]}

机构：

[1] Univ Newcastle, Ctr Bacterial Cell Biol, Inst Cell & Mol Biosci, Sch Med, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England

来源：

NATURE REVIEWS MICROBIOLOGY | 2009年 / 7卷 / 09期

基金：

英国生物技术与生命科学研究理事会;

关键词：

MEMBRANE TARGETING SEQUENCE; FTSZ-INTERACTING PROTEIN; SPIRAL-LIKE INTERMEDIATE; ESCHERICHIA-COLI FTSA; SITE SELECTION SYSTEM; C-TERMINAL TAIL; BACILLUS-SUBTILIS; SEPTAL RING; CRYSTAL-STRUCTURE; CONFORMATIONAL-CHANGE;

D O I：

10.1038/nrmicro2198

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学];

摘要：

Bacterial cell division is orchestrated by a tubulin homologue, FtsZ, which polymerizes to form a ring-like structure that is both a scaffold for the assembly of the bacterial cytokinetic machinery and, at least in part, a source of the energy for constriction. FtsZ assembly is tightly regulated, and a diverse repertoire of accessory proteins contributes to the formation of a functional division machine that is responsive to cell cycle status and environmental stress. In this Review, we describe the interaction of these proteins with FtsZ and discuss recent advances in our understanding of Z ring assembly.

引用

页码：642 / 653

页数：12

共 156 条

[1]

Maturation of the Escherichia coli divisome occurs in two steps [J].