Azithromycin failure in Mycoplasma genitalium urethritis

被引：128

作者：

Bradshaw, CS

Jensen, JS

Tabrizi, SN

Read, TRH

Garland, SM

Hopkins, CA

Moss, LM

Fairley, CK

机构：

[1] Univ Melbourne, Parkville, Vic 3052, Australia

[2] State Serum Inst, Copenhagen, Denmark

来源：

EMERGING INFECTIOUS DISEASES | 2006年 / 12卷 / 07期

关键词：

D O I：

10.3201/eid1207.051558

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report significant failure rates (28%, 95% confidence interval 15%-45%) after administering 1 g azithromycin to men with Mycoplasma genitalium-positive nongonococcal urethritis. In vitro evidence supported reduced susceptibility of M. genitalium to macrolides. Moxifloxacin administration resulted in rapid symptom resolution and eradication of infection in all-cases. These findings have implications for management of urethritis.

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收藏

页码：1149 / 1152

页数：4

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