High Sensitivity and Specificity of Acid-Fast Microscopy for Diagnosis of Pulmonary Tuberculosis in an African Population with a High Prevalence of Human Immunodeficiency Virus

被引：15

作者：

Shea, Yvonne R. ^{[1
]}

Davis, J. Lucian ^{[2
,3
,4
]}

Huang, Laurence ^{[2
,3
,4
]}

Kovacs, Joseph A. ^{[5
]}

Masur, Henry ^{[5
]}

Mulindwa, Francis ^{[4
,6
]}

Opus, Sally ^{[4
,6
]}

Chow, Yuenwah ^{[1
]}

Murray, Patrick R. ^{[1
]}

机构：

[1] NIH, Dept Lab Med, Ctr Clin, Bethesda, MD 20892 USA

[2] San Francisco Gen Hosp, Dept Med, San Francisco, CA 94110 USA

[3] Univ Calif San Francisco, San Francisco, CA 94143 USA

[4] Univ Calif San Francisco Res Collaborat, Makerere Univ, Kampala, Uganda

[5] NIH, Dept Crit Care Med, Ctr Clin, Bethesda, MD 20892 USA

[6] Mulago Hosp, Kampala, Uganda

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2009年 / 47卷 / 05期

关键词：

SPUTUM SMEAR MICROSCOPY; FLUORESCENCE; SECA1;

D O I：

10.1128/JCM.00348-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Laboratories in low-income countries report that acid-fast microscopy is insensitive and nonspecific. We demonstrate that for a Ugandan population with high prevalences of tuberculosis and human immunodeficiency virus infection, acid-fast microscopy is highly sensitive (93.1%) and specific (100%) when performed by trained technologists in a carefully controlled manner using established techniques.

引用

页码：1553 / 1555

页数：3

共 12 条

[1]

[Anonymous], SPEC COURT SIERR LEO

[2] Polymerase Chain Reaction of secA1 on Sputum or Oral Wash Samples for the Diagnosis of Pulmonary Tuberculosis [J].

Davis, J. Lucian ;

Huang, Laurence ;

Kovacs, Joseph A. ;

Masur, Henry ;

Murray, Patrick ;

Havlir, Diane V. ;

Worodria, William O. ;

Charlebois, Edwin D. ;

Srikantiah, Padmini ;

Cattamanchi, Adithya ;

Huber, Charles ;

Shea, Yvonne R. ;

Chow, Yuenwah ;

Fischer, Steven H. .

CLINICAL INFECTIOUS DISEASES, 2009, 48 (06) :725-732

[3]

Kent P. T, 1985, PUBLIC HLTH MYCOBACT

[4] Use of light-emitting diode fluorescence microscopy to detect acid-fast bacilli in sputum [J].

Marais, Ben J. ;

Brittle, Wendy ;

Painczyk, Katrien ;

Hesseling, Anneke C. ;

Beyers, Nulda ;

Wasserman, Elizabeth ;

van Soolingen, Dick ;

Warren, Rob M. .

CLINICAL INFECTIOUS DISEASES, 2008, 47 (02) :203-207

[5] THE ACID-FAST STAIN - A SPECIFIC AND PREDICTIVE TEST FOR MYCOBACTERIAL DISEASE [J].

MURRAY, PR ;

ELMORE, C ;

KROGSTAD, DJ .

ANNALS OF INTERNAL MEDICINE, 1980, 92 (04) :512-513

[6] Fluorescence versus conventional sputum smear microscopy for tuberculosis: a systematic review [J].

R Steingart, Karen ;

Henry, Megan ;

Ng, Vivienne ;

Hopewell, Philip C. ;

Ramsay, Andrew ;

Cunningham, Jane ;

Urbanczik, Richard ;

Perkins, Mark ;

Aziz, Mohamed Abdel ;

Pai, Madhukar .

LANCET INFECTIOUS DISEASES, 2006, 6 (09) :570-581

[7] Lessons from a proficiency testing event for acid-fast microscopy [J].

Somoskövi, A ;

Hotaling, JE ;

Fitzgerald, M ;

O'Donnell, D ;

Parsons, LM ;

Salfinger, M .

CHEST, 2001, 120 (01) :250-257

[8] Sputum processing methods to improve the sensitivity of smear microscopy for tuberculosis: a systematic review [J].

Steingart, Karen R. ;

Ng, Vivienne ;

Henry, Megan ;

Hopewell, Philip C. ;

Ramsay, Andrew ;

Cunningham, Jane ;

Urbanczik, Richard ;

Perkins, Mark D. ;

Aziz, Mohamed Abdel ;

Pai, Madhukar .

LANCET INFECTIOUS DISEASES, 2006, 6 (10) :664-674

[9]

Toman K., 2004, Toman's Tuberculosis Case Detection, Treatment and Monitoring: Questions and Answers, V2nd edn, P11

[10]

Van Deun A, 2005, INT J TUBERC LUNG D, V9, P1127

← 1 2 →