Absolute versus relative caloric intake - Clues to the mechanism of calorie/aging-rate interactions

被引：3

作者：

Anson, RM ^{[1
]}

机构：

[1] Windward Isl Res Inst, St Georges, Grenada

[2] St Georges Univ, St Georges, Grenada

来源：

STRATEGIES FOR ENGINEERED NEGLIGIBLE SENESCENCE: WHY GENUINE CONTROL OF AGING MAY BE FORESEEABLE | 2004年 / 1019卷

关键词：

caloric restriction; dietary restriction; aging; fasting; energy; calories; life span; longevity; animal models;

D O I：

10.1196/annals.1297.076

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

It has been suggested that the influence of caloric intake on aging rate is not due to the absolute number of calories ingested. Instead, aging rate is altered only when there is a disparity between the actual caloric intake and that which would be ingested if the food supply were unlimited. This review will discuss a few of the studies supporting this viewpoint.

引用

收藏

页码：427 / 429

页数：3

相关论文

共 9 条

[1]

Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake [J].

Anson, RM ;

Guo, ZH ;

de Cabo, R ;

Iyun, T ;

Rios, M ;

Hagepanos, A ;

Ingram, DK ;

Lane, MA ;

Mattson, MP .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (10) :6216-6220

[2]

EFFECTS OF INTERMITTENT FEEDING UPON BODY-WEIGHT AND LIFE-SPAN IN INBRED MICE - INTERACTION OF GENOTYPE AND AGE [J].

GOODRICK, CL ;

INGRAM, DK ;

REYNOLDS, MA ;

FREEMAN, JR ;

CIDER, N .

MECHANISMS OF AGEING AND DEVELOPMENT, 1990, 55 (01) :69-87

[3]

EFFECTS OF FOOD RESTRICTION ON AGING - SEPARATION OF FOOD-INTAKE AND ADIPOSITY [J].

HARRISON, DE ;

ARCHER, JR ;

ASTLE, CM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (06) :1835-1838

[4]

LONGEVITY OF COLD-EXPOSED RATS - A REEVALUATION OF THE RATE-OF-LIVING THEORY [J].

HOLLOSZY, JO ;

SMITH, EK .

JOURNAL OF APPLIED PHYSIOLOGY, 1986, 61 (05) :1656-1660

[5]

The effects of diet, ad libitum feeding, and moderate and severe dietary restriction on body weight, survival, clinical pathology parameters, and cause of death in control Sprague-Dawley rats [J].

Hubert, MF ;

Laroque, P ;

Gillet, JP ;

Keenan, KP .

TOXICOLOGICAL SCIENCES, 2000, 58 (01) :195-207

[6]

Ingram D K, 1987, Basic Life Sci, V42, P247

[7]

Effects of caloric restriction or augmentation in adult rats: Longevity and lesion biomarkers of aging [J].

Lipman, RD ;

Smith, DE ;

Blumberg, JB ;

Bronson, RT .

AGING CLINICAL AND EXPERIMENTAL RESEARCH, 1998, 10 (06) :463-470

[8]

ACTION OF FOOD RESTRICTION IN DELAYING THE AGING PROCESS [J].

MASORO, EJ ;

YU, BP ;

BERTRAND, HA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (13) :4239-4241

[9]

The effect of retarded growth upon the length of life span and upon the ultimate body size [J].

McCay, CM ;

Crowell, MF ;

Maynard, LA .

JOURNAL OF NUTRITION, 1935, 10 (01) :63-79