The sweet side of biomarker discovery

被引：27

作者：

Bosques, Carlos J. ^{[1
]}

Raguram, S. ^{[1
]}

Sasisekharan, Ram ^{[1
]}

机构：

[1] Harvard MIT Div Hlth Sci & Technol, Biol Engn Div, Ctr Environm Hlth Sci, Ctr Biomed Engn, Cambridge, MA 02139 USA

来源：

NATURE BIOTECHNOLOGY | 2006年 / 24卷 / 09期

关键词：

D O I：

10.1038/nbt0906-1100

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Glycomics offers exciting possibilities for discovering serum biomarkers.

引用

页码：1100 / 1101

页数：3

共 10 条

[1] Profiling of glycans in serum for the discovery of potential biomarkers for ovarian cancer [J].

An, Hyun Joo ;

Miyamoto, Suzanne ;

Lancaster, Katherine S. ;

Kirmiz, Crystal ;

Li, Bensheng ;

Lam, Kit S. ;

Leiserowitz, Gary S. ;

Lebrilla, Carlito B. .

JOURNAL OF PROTEOME RESEARCH, 2006, 5 (07) :1626-1635

[2] Detailed glycan analysis of serum glycoproteins of patients with congenital disorders of glycosylation indicates the specific defective glycan processing step and provides an insight into pathogenesis [J].

Butler, M ;

Quelhas, D ;

Critchley, AJ ;

Carchon, H ;

Hebestreit, HF ;

Hibbert, RG ;

Vilarinho, L ;

Teles, E ;

Matthijs, G ;

Schollen, E ;

Argibay, P ;

Harvey, DJ ;

Dwek, RA ;

Jaeken, J ;

Rudd, PM .

GLYCOBIOLOGY, 2003, 13 (09) :601-622

[3] Noninvasive diagnosis of liver cirrhosis using DNA sequencer-based total serum protein glycomics [J].

Callewaert, N ;

Van Vlierberghe, H ;

Van Hecke, A ;

Laroy, W ;

Delanghe, J ;

Contreras, R .

NATURE MEDICINE, 2004, 10 (04) :429-434

[4] Glycoprotein glycosylation and cancer progression [J].

Dennis, JW ;

Granovsky, M ;

Warren, CE .

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1999, 1473 (01) :21-34

[5] BETA-1-6 BRANCHING OF ASN-LINKED OLIGOSACCHARIDES IS DIRECTLY ASSOCIATED WITH METASTASIS [J].

DENNIS, JW ;

LAFERTE, S ;

WAGHORNE, C ;

BREITMAN, ML ;

KERBEL, RS .

SCIENCE, 1987, 236 (4801) :582-585

[6] Glycans in cancer and inflammation. Potential for therapeutics and diagnostics [J].

Dube, DH ;

Bertozzi, CR .

NATURE REVIEWS DRUG DISCOVERY, 2005, 4 (06) :477-488

[7] The sweet and sour of cancer: Glycans as novel therapeutic targets [J].

Fuster, MM ;

Esko, JD .

NATURE REVIEWS CANCER, 2005, 5 (07) :526-542

[8] A serum glycomics approach to breast cancer biomarkers [J].

Kirmiz, Crystal ;

Li, Bensheng ;

An, Hyun Joo ;

Clowers, Brian H. ;

Chew, Helen K. ;

Lam, Kit S. ;

Ferrige, Anthony ;

Alecio, Robert ;

Borowsky, Alexander D. ;

Sulaimon, Shola ;

Lebrilla, Carlito B. ;

Miyamoto, Suzanne .

MOLECULAR & CELLULAR PROTEOMICS, 2007, 6 (01) :43-55

[9] Glycomics: an integrated systems approach to structure-function relationships of glycans [J].

Raman, R ;

Raguram, S ;

Venkataraman, G ;

Paulson, JC ;

Sasisekharan, R .

NATURE METHODS, 2005, 2 (11) :817-824

[10]

Shimodaira K, 1997, CANCER RES, V57, P5201

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