An immunologically active arabinogalactan from Tinospora cordifolia

被引：86

作者：

Chintalwar, G ^{[1
]}

Jain, A

Sipahimalani, A

Banerji, A

Sumariwalla, P

Ramakrishnan, R

Sainis, K

机构：

[1] Bhabha Atom Res Ctr, Div Bioorgan, Modular Labs, Trombay 400085, Mumbai, India

[2] Bhabha Atom Res Ctr, Div Cell Biol, Modular Labs, Trombay 400085, Mumbai, India

来源：

PHYTOCHEMISTRY | 1999年 / 52卷 / 06期

关键词：

Tinospora cordifolia; Menispermaceae; acidic arabinogalactan; isolation; structure; immunological activity;

D O I：

10.1016/S0031-9422(99)00386-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An arabinogalactan of mean M-r 2.2 x 10(6) has been isolated from the dried stems of Tinospora cordifolia and examined by methylation analysis, partial hydrolysis and carboxyl reduction. Purified polysaccharide showed polyclonal mitogenic activity against B-cells, their proliferation did not require macrophages. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：1089 / 1093

页数：5

共 15 条

[1] A MODIFIED URONIC ACID CARBAZOLE REACTION [J].

BITTER, T ;

MUIR, HM .

ANALYTICAL BIOCHEMISTRY, 1962, 4 (04) :330-&

[2] CORDIFOLISIDE-A, CORDIFOLISIDE-B, CORDIFOLISIDE-C - NORDITERPENE FURAN GLYCOSIDES FROM TINOSPORA-CORDIFOLIA [J].

GANGAN, VD ;

PRADHAN, P ;

SIPAHIMALANI, AT ;

BANERJI, A .

PHYTOCHEMISTRY, 1994, 37 (03) :781-786

[3] NORDITERPENE FURAN GLYCOSIDES FROM TINOSPORA-CORDIFOLIA [J].

GANGAN, VD ;

PRADHAN, P ;

SIPAHIMALANI, AT ;

BANERJI, A .

PHYTOCHEMISTRY, 1995, 39 (05) :1139-1142

[4]

Gangan VD, 1997, INDIAN J CHEM B, V36, P787

[5]

Gangan VD, 1996, INDIAN J CHEM B, V35, P630

[6]

HAKOMORI SI, 1964, J BIOCHEM-TOKYO, V55, P205

[7]

KIRTIKAR KR, 1933, INDIAN MED PLANTS, V1, P77

[8]

Sainis K.B., 1997, IMMUNOMODULATION, P155

[9] PHENYLPROPANOID GLYCOSIDES AND TETRAHYDROFUROFURANLIGNAN GLYCOSIDES FROM THE ADAPTOGENIC PLANT DRUGS TINOSPORA-CORDIFOLA AND DRYPETES-ROXBURGHII [J].

SIPAHIMALANI, A ;

NORR, H ;

WAGNER, H .

PLANTA MEDICA, 1994, 60 (06) :596-597

[10] STOICHIOMETRIC DEPOLYMERIZATION OF POLYURONIDES AND GLYCOSAMINOGLYCURONANS TO MONOSACCHARIDES FOLLOWING REDUCTION OF THEIR CARBODIIMIDE-ACTIVATED CARBOXYL GROUPS [J].

TAYLOR, RL ;

CONRAD, HE .

BIOCHEMISTRY, 1972, 11 (08) :1383-&

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