Cationic planar chiral palladium PS complexes as highly efficient catalysts in the enantioselective ring opening of oxa- and azabicyclic alkenes

被引：87

作者：

Cabrera, S ^{[1
]}

Arrayás, RG ^{[1
]}

Carretero, JC ^{[1
]}

机构：

[1] Univ Autonoma Madrid, Fac Ciencias, Dept Quim Organ, E-28049 Madrid, Spain

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 30期

关键词：

alkenes; asymmetric catalysis; ferrocenyl ligands; phenylsilyl; palladium; S ligands;

D O I：

10.1002/anie.200460087

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Open plan: Cationic methylpalladium(II) complexes of planar chiral Fesulphos ligands (Fesulphos = 1-phosphanyl-2-sulfenylferrocene) show excellent performance in the alkylative ring opening of oxa- and azabicyclic alkenes with dialkyl zinc reagents (see scheme, Cy = cyclohexyl, ArF = 3,5-bis (trifluoromethyl)phenyl). Catalyst loadings as low as 0.5 mol% are normally sufficient to achieve high enantioselectivities (94- > 99% ee).

引用

页码：3944 / 3947

页数：4

共 22 条

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