Hypoglycaemic and other related actions of Tinospora cordifolia roots in alloxan-induced diabetic rats

被引：152

作者：

Stanely, P ^{[1
]}

Prince, M ^{[1
]}

Menon, VP ^{[1
]}

机构：

[1] Annamalai Univ, Dept Biochem, Annamalainagar 608002, Tamil Nadu, India

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2000年 / 70卷 / 01期

关键词：

Tinospora cordifolia; aqueous extract; alloxan diabetes; lipids; brain;

D O I：

10.1016/S0378-8741(99)00136-1

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Tinospora cordifolia is widely used in Indian Ayurvedic medicine for treating diabetes mellitus. Oral administration of an aqueous T. cordifolia root extract (TCREt) to alloxan diabetic rats caused a significant reduction in blood glucose and brain lipids. The extract caused an increase in body weight, total haemoglobin and hepatic hexokinase. The root extract also lowers hepatic glucose-6-phosphatase and serum acid phosphatase, alkaline phosphatase, and lactate dehydrogenase in diabetic rats. Thus TCREt has hypoglycaemic and hypolipidaemic effect. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：9 / 15

页数：7

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