Tyrosine 92 of aristolochene synthase directs cyclisation of farnesyl pyrophosphate

被引：30

作者：

Calvert, MJ ^{[1
]}

Taylor, SE ^{[1
]}

Allemann, RK ^{[1
]}

机构：

[1] Univ Birmingham, Sch Chem Engn, Birmingham B15 2TT, W Midlands, England

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 20期

关键词：

D O I：

10.1039/b206517g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A mutant of Aristolochene Synthase (AS), in which Tyr 92 was replaced by Val, produced the alicyclic beta-(E)-farnesene as the major product, indicating that cyclisation of FPP is controlled by Tyr 92 in AS.

引用

页码：2384 / 2385

页数：2

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