Non-spatial, motor-specific activation in posterior parietal cortex

被引:168
作者
Calton, JL [1 ]
Dickinson, AR [1 ]
Snyder, LH [1 ]
机构
[1] Washington Univ, Sch Med, Dept Anat & Neurobiol, St Louis, MO 63110 USA
关键词
D O I
10.1038/nn862
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
A localized cluster of neurons in macaque posterior parietal cortex, termed the parietal reach region (PRR), is activated when a reach is planned to a visible or remembered target. To explore the role of PRR in sensorimotor transformations, we tested whether cells would be activated when a reach is planned to an as-yet unspecified goal. Over one-third of PRR cells increased their firing after an instruction to prepare a reach, but not after an instruction to prepare a saccade, when the target of the movement remained unknown. A partially overlapping population (two-thirds of cells) was activated when the monkey was informed of the target location but not the type of movement to be made. Thus a subset of PRR neurons separately code spatial and effector-specific information, consistent with a role in specifying potential motor responses to particular targets.
引用
收藏
页码:580 / 588
页数:9
相关论文
共 49 条
  • [1] ENCODING OF SPATIAL LOCATION BY POSTERIOR PARIETAL NEURONS
    ANDERSEN, RA
    ESSICK, GK
    SIEGEL, RM
    [J]. SCIENCE, 1985, 230 (4724) : 456 - 458
  • [2] NEURONAL CORRELATES OF INFERRED MOTION IN PRIMATE POSTERIOR PARIETAL CARTER
    ASSAD, JA
    MAUNSELL, JHR
    [J]. NATURE, 1995, 373 (6514) : 518 - 521
  • [3] Modulation of neuronal activity by target uncertainty
    Basso, MA
    Wurtz, RH
    [J]. NATURE, 1997, 389 (6646) : 66 - 69
  • [4] Basso MA, 1998, J NEUROSCI, V18, P7519
  • [5] Early coding of reaching in the parietooccipital cortex
    Battaglia-Mayer, A
    Ferraina, S
    Mitsuda, T
    Marconi, B
    Genovesio, A
    Onorati, P
    Lacquaniti, F
    Caminiti, R
    [J]. JOURNAL OF NEUROPHYSIOLOGY, 2000, 83 (04) : 2374 - 2391
  • [6] Representation of the visual field in the lateral intraparietal area of macaque monkeys: a quantitative receptive field analysis
    Ben Hamed, S
    Duhamel, JR
    Bremmer, F
    Graf, W
    [J]. EXPERIMENTAL BRAIN RESEARCH, 2001, 140 (02) : 127 - 144
  • [7] Visual feature selectivity In frontal eye fields induced by experience in mature macaques
    Bichot, NP
    Schall, JD
    Thompson, KG
    [J]. NATURE, 1996, 381 (6584) : 697 - 699
  • [8] Gaze effects in the cerebral cortex: reference frames for space coding and action
    Boussaoud, D
    Bremmer, F
    [J]. EXPERIMENTAL BRAIN RESEARCH, 1999, 128 (1-2) : 170 - 180
  • [9] BEHAVIORAL ENHANCEMENT OF VISUAL RESPONSES IN MONKEY CEREBRAL-CORTEX .1. MODULATION IN POSTERIOR PARIETAL CORTEX RELATED TO SELECTIVE VISUAL-ATTENTION
    BUSHNELL, MC
    GOLDBERG, ME
    ROBINSON, DL
    [J]. JOURNAL OF NEUROPHYSIOLOGY, 1981, 46 (04) : 755 - 772
  • [10] Simultaneous encoding of multiple potential reach directions in dorsal premotor cortex
    Cisek, P
    Kalaska, JF
    [J]. JOURNAL OF NEUROPHYSIOLOGY, 2002, 87 (02) : 1149 - 1154