Tyrosine sulfation: a modulator of extracellular protein-protein interactions

被引：220

作者：

Kehoe, JW

Bertozzi, CR

机构：

[1] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA

[2] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

来源：

CHEMISTRY & BIOLOGY | 2000年 / 7卷 / 03期

关键词：

D O I：

10.1016/S1074-5521(00)00093-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Tyrosine sulfation is a post-translational modification of many secreted and membrane-bound proteins. Its biological roles have been unclear. Recent work has implicated tyrosine sulfate as a determinant of protein-protein interactions involved in leukocyte adhesion, hemostasis and chemokine signaling.

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页码：R57 / R61

页数：5

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