BCL2-specific inhibitor ABT-199 synergizes strongly with cytarabine against the early immature LOUCY cell line but not more-differentiated T- ALL cell lines

被引:51
作者
Anderson, N. M. [1 ]
Harrold, I. [1 ]
Mansour, M. R. [2 ,3 ]
Sanda, T. [4 ]
McKeown, M. [5 ]
Nagykary, N. [1 ]
Bradner, J. E. [5 ]
Zhang, G. Lan [6 ]
Look, A. T. [2 ]
Feng, H. [1 ]
机构
[1] Boston Univ, Sch Med, Sect Hematol & Med Oncol, Dept Pharmacol & Expt Therapeut,Ctr Canc Res, Boston, MA 02118 USA
[2] Dana Farber Canc Inst, Dept Pediat Oncol, Boston, MA 02115 USA
[3] UCL, Univ Coll London Canc Inst, Dept Haematol, London, England
[4] Natl Univ Singapore, Canc Sci Inst Singapore, Singapore 117548, Singapore
[5] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA
[6] Boston Univ, Dept Comp Sci, Metropolitan Coll, Boston, MA 02215 USA
关键词
ACUTE LYMPHOBLASTIC-LEUKEMIA; CANCER; POTENT; FAMILY;
D O I
10.1038/leu.2013.377
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
引用
收藏
页码:1145 / 1148
页数:5
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