Prognostic markers under watchful waiting and radical prostatectomy

被引:21
作者
Holmberg, Lars [1 ]
Bill-Axelson, Anna
Garmo, Hans
Palmgren, Juni
Norlen, Bo Johan
Adami, Hans Olov
Johansson, Jan Erik
机构
[1] Univ Uppsala Hosp, Reg Oncol Ctr, SE-75185 Uppsala, Sweden
[2] Univ Uppsala Hosp, Dept Surg Sci, SE-75185 Uppsala, Sweden
[3] Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden
[4] Harvard Univ, Sch Publ Hlth, Boston, MA 02115 USA
[5] Orebro Univ Hosp, Dept Urol, Orebro, Sweden
关键词
D O I
10.1016/j.hoc.2006.03.007
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A suitable setting to analyze factors that determine prognosis or treatment response in prostate cancer is an unbiased comparison of radical prostatectomy and watchful waiting as in die Scandinavian Prostate Cancer Group Trial number 4. In our previous presentation of 10-year results, we studied Gleason score, serum prostate-specific antigen (PSA) at diagnosis, and age at diagnosis as modifiers of the effect of radical prostatectomy on survival. Because overall prognostic information obtained by these parameters or by tumor stage was not provided in our publication, we now present these data in the two study arms separately.
引用
收藏
页码:845 / +
页数:12
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