Oligonucleotide labeling methods .4. Direct labeling reagents with a novel, non-nucleosidic, chirally defined 2-deoxy-beta-D-ribosyl backbone.

被引：14

作者：

Smith, TH ^{[1
]}

Kent, MA ^{[1
]}

Muthini, S ^{[1
]}

Boone, SJ ^{[1
]}

Nelson, PS ^{[1
]}

机构：

[1] CLONTECH LABS INC,NUCLE ACIDS CHEM DIV,PALO ALTO,CA 94303

来源：

NUCLEOSIDES & NUCLEOTIDES | 1996年 / 15卷 / 10期

关键词：

D O I：

10.1080/07328319608002458

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Novel solid supports and CE-phosphoramidite reagents have been prepared featuring a unique 2'-deoxyribosyl backbone. These chirally pure reagents form the basis of an oligonucleotide labeling system which provides diastereomerically pure oligonucleotides.

引用

页码：1581 / 1594

页数：14

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