Industrial applications of enzyme biocatalysis: Current status and future aspects

被引:733
作者
Choi, Jung-Min [1 ]
Han, Sang-Soo [1 ]
Kim, Hak-Sung [1 ]
机构
[1] Korea Adv Inst Sci & Technol, Dept Biol Sci, Taejon 305701, South Korea
基金
新加坡国家研究基金会;
关键词
Enzymes; Industrial applications; Biocatalysis; Bioprocess; ITERATIVE SATURATION MUTAGENESIS; DIRECTED EVOLUTION; ASPERGILLUS-NIGER; EPOXIDE HYDROLASE; GALACTO-OLIGOSACCHARIDES; BETA-GALACTOSIDASE; NITRILE HYDRATASE; ENANTIOSELECTIVE HYDROLYSIS; COMPUTATIONAL DESIGN; ENHANCED PRODUCTION;
D O I
10.1016/j.biotechadv.2015.02.014
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 [微生物学]; 090105 [作物生产系统与生态工程];
摘要
Enzymes are the most proficient catalysts, offering much more competitive processes compared to chemical catalysts. The number of industrial applications for-enzymes has exploded in recent years, mainly owing to advances in protein engineering technology and environmental and economic necessities. Herein, we review recent progress in enzyme biocatalysis, and discuss the trends and strategies that are leading to broader industrial enzyme applications. The challenges and opportunities in developing biocatalytic processes are also discussed. (C) 2015 Elsevier Inc. All rights reserved.
引用
收藏
页码:1443 / 1454
页数:12
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