Absence in Helicobacter pylori of an uptake sequence for enhancing uptake of homospecific DNA during transformation

被引：26

作者：

Saunders, NJ ^{[1
]}

Peden, JF

Moxon, ER

机构：

[1] Univ Oxford, Inst Mol Med, Mol Infect Dis Grp, Oxford OX3 9DS, England

[2] Univ Oxford, Sir William Dunn Sch Pathol, Bioinformat Ctr, Oxford OX1 3RE, England

来源：

MICROBIOLOGY-SGM | 1999年 / 145卷

基金：

英国惠康基金;

关键词：

uptake sequence; Helicobacter pylori; transformation;

D O I：

10.1099/00221287-145-12-3523

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Uptake sequences are abundant sequence motifs, often located downstream of ORFs. that are used to facilitate the within-species horizontal transfer of DNA. A frequent word analysis of the complete genome sequence of Helicobacter pylori strain 26685 was performed to search for and determine the identity of an uptake sequence in this species. The results demonstrated that Hel. pylori does not possess an uptake sequence. This is the first naturally transformable Gram-negative species shown to lack such a transformation-targeting system.

引用

页码：3523 / 3528

页数：6

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