Electrochemical study of cystine in the presence of cadmium and folic acid

被引：20

作者：

Çakir, S ^{[1
]}

Biçer, E ^{[1
]}

Çakir, O ^{[1
]}

机构：

[1] Ondokuz Mayis Univ, Fac Arts & Sci, Dept Chem, TR-55139 Kurupelit, Turkey

来源：

JOURNAL OF INORGANIC BIOCHEMISTRY | 1999年 / 77卷 / 3-4期

关键词：

cystine; cadmium; folic acid; electrochemistry; interfacial interactions;

D O I：

10.1016/S0162-0134(99)00207-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The cyclic voltammetric behaviour of cystine (RSSR) was studied on a static mercury drop electrode (SMDE) in the hanging mercury drop elecrode (HMDE) mode at pH 7.4. RSSR gave two peaks at -0.106 V (mercuric cysteine thiolate, RS-Hg-SR) and -0.552 V (mercurous cysteine thiolate, RS-HgHg-SR), respectively. The electrochemical behaviour of complexes of RSSR or folic acid with cadmium(II), and cadmium(II)-cysteinate (Cd(SR)(2)) complex in the presence of folic acid was also investigated. Experimental results show that the Cd(SR)(2) complex forms a peak at -0.808 V on the mercury electrode surface. Also, the electroreduction of the cadmium(II)-folic acid complex occurs at -0.722 V. These complexes are reduced at a more negative potential than that of the foe cadmium ion. When folic acid is added to RSSR solution, it causes shifts of the voltammetric reduction peaks of RS-Hg-SR and RS-HgHg-SR towards positive potentials. The shifts are invariably accompanied by a decrease of peak currents. This is explained as due to the formation of adducts between folic acid and cysteine thiolate (reduction product RS-) at the electrode surface. Analogous results were observed between folic acid and Cd(SR)(2) complex, and were ascribed to the same cause. (C)1999 Elsevier Science Inc. All rights reserved.

引用

页码：249 / 255

页数：7

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