Notch signaling in stem cell systems

被引：331

作者：

Chiba, Shigeru ^{[1
]}

机构：

[1] Univ Tokyo, Dept Cell Therapy & Transplantat Med, Bunkyo Ku, Tokyo 1138655, Japan

来源：

STEM CELLS | 2006年 / 24卷 / 11期

关键词：

stem cell; notch; embryogenesis; homeostasis;

D O I：

10.1634/stemcells.2005-0661

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

The Notch signaling pathway is among the most commonly used communication channels in animal cells. Recent studies have demonstrated that this pathway is indispensable for cells in various stages of maturation, including terminal differentiation. One main focus in mammalian studies is the role of Notch in embryonic and postembryonic stem cell systems. In this review, the roles of Notch signaling in various mammalian stem and early progenitor cells are summarized.

引用

页码：2437 / 2447

页数：11

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