Carbocyclisation of alkynes with external nucleophiles catalysed by gold, platinum and other electrophilic metals

被引：266

作者：

Abu Sohel, Shariar Md. ^{[1
]}

Liu, Rai-Shung ^{[1
]}

机构：

[1] Natl Tsing Hua Univ, Dept Chem, Hsinchu, Taiwan

来源：

CHEMICAL SOCIETY REVIEWS | 2009年 / 38卷 / 08期

关键词：

CONTAINING CARBONYL YLIDES; HYDRATIVE CYCLIZATION; 4+2 CYCLOADDITION; C-C; CYCLOISOMERIZATIONS; CARBOCYCLIZATION; GENERATION; HYDROXYCYCLIZATION; ALKOXYCYCLIZATION; CONSTRUCTION;

D O I：

10.1039/b807499m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This tutorial review covers recent developments in catalytic carbocyclisation of functionalised alkynes with external nucleophiles catalysed by gold, platinum and other electrophilic metals. Substrates of such reactions require a tethered functionality to react with the alkyne to complete a carbocyclic ring. We classify the reactions according to the tethered functionalities to illustrate the diversity of the carbocyclisations; these substrates include: (1) alkyne-alkyne, (2) alkyne-allene, (3) alkyne-alkene, (4) oxo-alkynes and (5) oxo-diynes and triynes. Besides their mechanistic interest, these reactions meet atom economy criteria because complex and functionalised carbocyclic products are easily assembled in a cascade sequence from readily available alkynes and nucleophiles.

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页码：2269 / 2281

页数：13

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