Evolution of resistance patterns and identification of risk factors for Streptococcus pneumoniae colonisation in daycare centre attendees in Athens, Greece

被引：6

作者：

Volonakis, Katerina ^{[1
]}

Souli, Maria ^{[1
]}

Kapaskelis, Anastassios ^{[1
]}

Baziaka, Fotini ^{[1
]}

Grammelis, Vassilios ^{[1
]}

Ziakas, Panayiotis D. ^{[1
]}

Giamarellou, Helen ^{[1
]}

机构：

[1] Univ Athens, Gen Hosp Attikon, Sch Med, Dept Internal Med 4, Chaidari 12462, Greece

来源：

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 2006年 / 28卷 / 04期

关键词：

Streptococcus pneumoniae; surveillance; colonisation; daycare centres;

D O I：

10.1016/j.ijantimicag.2006.07.002

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Two cross-sectional surveillance studies were conducted during the winters of 2000 and 2003 in Athens, Greece, to obtain nasopharyngeal swabs from healthy pre-school children attending kindergartens. A total of 460 strains were examined in 2000 and 485 strains in 2003, with carriage rates of 31.7% and 34.6%, respectively. Susceptibility patterns were evaluated for penicillin G, erythromycin, ceftriaxone, moxifloxacin, linezolid and telithromycin. Penicillin non-susceptibility increased from 20% to 34.9%, whereas erythromycin non-susceptibility increased from 23% to 30.5%. Resistance to both agents climbed from 7.5% to 22.3% (P < 0.001). No isolates were found to be resistant to any of the other antimicrobial agents. Risk factors for carriage and/or antimicrobial resistance were also assessed. (c) 2006 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.

引用

页码：297 / 301

页数：5

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