Hormesis - An inappropriate extrapolation from the specific to the universal

被引：35

作者：

Axelrod, D

Burns, K

Davis, D

Von Larebeke, N

机构：

[1] NYU, Med Ctr, Clin Breast Serv, Community Canc Educ & Outreach, New York, NY USA

[2] Abt Associates Inc, Environm Res Area, Cambridge, England

[3] Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA USA

[4] Univ Pittsburgh, Inst Canc, Ctr Environm ecol, Pittsburgh, PA USA

[5] Ghent Univ Hosp, Dept Radiotherapy Nucl Med & Expt Cancerol, Study Ctr Carcinogenesis & Primary Prevent Canc, B-9000 Ghent, Belgium

来源：

INTERNATIONAL JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH | 2004年 / 10卷 / 03期

关键词：

hormesis; risk assessment;

D O I：

10.1179/oeh.2004.10.3.335

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Although it is generally accepted that some chemicals may have beneficial effects at low doses, incorporating the se effects into risk assessments generally ignores well-established factors related to exposure and human susceptibility. The authors argue against indiscriminate application of hormesis in assessments of chemical risks for regulatory purposes.

引用

页码：335 / 339

页数：5

共 43 条

[1]

*ATSDR, 1999, TOX PROF LEAD HLTH E

[2] Toxicology rethinks its central belief - Hormesis demands a reappraisal of the way risks are assessed. [J].