Affective lability in patients with bipolar disorders is associated with high levels of childhood trauma

被引：45

作者：

Aas, Monica ^{[1
,2
]}

Aminoff, Sofie R. ^{[2
,3
]}

Lagerberg, Trine Vik ^{[2
]}

Etain, Bruno ^{[4
,5
,6
,7
]}

Agartz, Ingrid ^{[1
,8
]}

Andreassen, Ole A. ^{[1
,2
,7
]}

Melle, Ingrid ^{[1
,2
]}

机构：

[1] Univ Oslo, NORMENT, Inst Clin Med, N-0316 Oslo, Norway

[2] Oslo Univ Hosp, Div Mental Hlth & Addict, Psychosis Res Unit, Oslo, Norway

[3] Akershus Univ Hosp, Dept Specialized Inpatient Treatment, Lorenskog, Norway

[4] Hop H Mondor A Chenevier, AP HP, F-94000 Creteil, France

[5] INSERM, F-94000 Creteil, France

[6] Fdn Fondamental, Creteil, France

[7] ENBREC, Paris, France

[8] Diakonhjemmet Hosp, Dept Psychiat Res, Oslo, Norway

来源：

PSYCHIATRY RESEARCH | 2014年 / 218卷 / 1-2期

关键词：

Childhood Trauma Questionnaire (CTQ); Affective Lability Scale (ALS); Bipolar disorders; BORDERLINE PERSONALITY; AFFECTIVE INSTABILITY; AMYGDALA; REACTIVITY; COGNITION;

D O I：

10.1016/j.psychres.2014.03.046

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

This study aimed to investigate associations between a history of childhood trauma and levels of affective lability in bipolar patients compared to controls. Forty-two patients and 14 controls were assessed using the Affective Lability Scale (ALS) and the Childhood Trauma Questionnaire (CTQ). Affective Lability Score was significantly associated with scores on the Childhood Trauma Questionnaire. A multivariate regression model indicated a relationship between childhood trauma scores and differences in affective lability between patients and controls. (C) 2014 Elsevier Ireland Ltd. All rights reserved.

引用

页码：252 / 255

页数：4

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