Recent highlights in stationary phase design for open-tubular capillary electrochromatography

被引:117
作者
Guihen, E [1 ]
Glennon, JD [1 ]
机构
[1] Univ Coll Cork, ABCRF, Dept Chem, Cork, Ireland
关键词
reviews; stationary phases; electrochromatography; molecular imprinting; chip technology;
D O I
10.1016/j.chroma.2004.05.107
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This review examines the most recent innovations made to achieve high performance in open-tubular capillary electrochromatography (OT-CEC) separations, focusing on the ingenious chemical and physical solutions made to increase the surface area and equip the stationary phase with exploitable selectivity. Among the approaches taken are chemically bonded ligands, etching with chemical bonding, sol-gels, molecularly imprinted polymers, porous layers, physically attached or adsorbed phases, and nanoparticle coatings. Particularly noteworthy are modern developments with macrocyclic receptor ligands, nanoparticles and open channel electrochromatography on-chip. (C) 2004 Published by Elsevier B.V.
引用
收藏
页码:67 / 81
页数:15
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