Use of ethanol locks to prevent recurrent central line sepsis

被引：86

作者：

Metcalf, SCL ^{[1
]}

Chambers, ST ^{[1
]}

Pithie, AD ^{[1
]}

机构：

[1] Christchurch Hosp, Dept Infect Dis, Christchurch, New Zealand

来源：

JOURNAL OF INFECTION | 2004年 / 49卷 / 01期

关键词：

central line sepsis; ethanol;

D O I：

10.1016/j.jinf.2003.08.010

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Catheter-related sepsis (CRS) is a common complication of long-term parenteral nutrition. Conventional antibiotic therapy is often effective in the short-term but, because of poor activity against intraluminal microbial biofilms, may not prevent relapse. Ethanol is an effective antiseptic. We describe a case of a patient with recurrent CRS successfully treated with 70% ethanol locks. (C) 2003 The British Infection Society. Published by Elsevier Ltd. All rights reserved.

引用

页码：20 / 22

页数：3

共 11 条

[1] The promise of novel technology for the prevention of intravascular device-related bloodstream infection. II. Long-term devices [J].

Crnich, CJ ;

Maki, DG .

CLINICAL INFECTIOUS DISEASES, 2002, 34 (10) :1362-1368

[2]

DECICCO M, 1989, LANCET, V2, P1258, DOI 10.1016/S0140-6736(89)91861-8

[3] Biofilm formation: A clinically relevant microbiological process [J].

Donlan, RM .

CLINICAL INFECTIOUS DISEASES, 2001, 33 (08) :1387-1392

[4]

INGRAM LO, 1984, ADV MICROB PHYSIOL, V25, P253

[5] COMPLICATIONS OF INTRAVENOUS-FEEDING CATHETERS [J].

MUGHAL, MM .

BRITISH JOURNAL OF SURGERY, 1989, 76 (01) :15-21

[6] ETHANOL LOCK IN THE MANAGEMENT OF CATHETER OCCLUSION [J].

PENNINGTON, CR ;

PITHIE, AD .

JOURNAL OF PARENTERAL AND ENTERAL NUTRITION, 1987, 11 (05) :507-508

[7] Intravascular-catheter-related infections [J].

Raad, I .

LANCET, 1998, 351 (9106) :893-898

[8] A clinical trial on the prevention of catheter-related sepsis using a new hub model [J].

Segura, M ;

AlvarezLerma, F ;

Tellado, JM ;

JimenezFerreres, J ;

Oms, L ;

Rello, J ;

Baro, T ;

Sanchez, R ;

Morera, A ;

Mariscal, D ;

Marrugat, J ;

SitgesSerra, A .

ANNALS OF SURGERY, 1996, 223 (04) :363-369

[9] Inhibition by ethanol of the growth of biofilm and dispersed microcosm dental plaques [J].

Sissons, CH ;

Wong, L ;

Cutress, TW .

ARCHIVES OF ORAL BIOLOGY, 1996, 41 (01) :27-34

[10] Antibiotic resistance of bacteria in biofilms [J].

Stewart, PS ;

Costerton, JW .

LANCET, 2001, 358 (9276) :135-138

← 1 2 →