The lethality of Euphorbia conspicua to adults of Biomphalaria glabrata, cercaria of Schistosoma mansoni and larvae of Artemia salina

被引:28
作者
dos Santos, Aldenir F.
de Azevedo, Denise P. L.
Mata, Rosalina da C. dos Santos
de Mendonca, Dina I. M. Dinis
Sant'Ana, Antnio E. Goulart [1 ]
机构
[1] Univ Fed Alagoas, Dept Chem, BR-57092970 Maceio, AL, Brazil
[2] Agostinho Neto Univ, Dept Chem, Luanda, Angola
[3] Univ Beira Interior, Text & Paper Mat Ctr, P-6200001 Covilha, Portugal
[4] Univ Beira Interior, Dept Chem, P-6200001 Covilha, Portugal
关键词
latex; diterpenes; Molluscicide; Cercaricide; brine shrimp toxicity assay; Euphorbia conspicua;
D O I
10.1016/j.biortech.2005.11.020
中图分类号
S2 [农业工程];
学科分类号
0828 [农业工程];
摘要
Leaf extracts of Euphorbia conspicua (Euphorbiaceae), together with the latex and fractions derived therefrom, were evaluated for their molluscicidal and cercaricidal activities and their toxicities to brine shrimps. Whilst the leaf extracts were inactive against Biomphalaria glabrata, the latex, its triterpenic fraction and irritant fractions I and II exhibited high activities against adult snails with LC90 values of 4.87, 10.55, 0.64 and 0.10 mu g/mL, respectively. The latex and its derived fractions were considered lethal to the cercaria of Schistosoma mansoni at concentrations of 100 mu g/mL. The toxicities of the latex and the irritant fractions, but not of the triterpenic fraction, against Artemia salina were high with LC50 values < 10 mu g/mL. The possible application of the latex of E. conspicua as an alternative natural molluscicide is considered. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:135 / 139
页数:5
相关论文
共 34 条
[1]
A method of computing the effectiveness of an insecticide [J].
Abbott, WS .
JOURNAL OF ECONOMIC ENTOMOLOGY, 1925, 18 :265-267
[2]
INVESTIGATIONS OF MOLLUSCICIDAL ACTIVITY OF CERTAIN SUDANESE PLANTS USED IN FOLK-MEDICINE .4. [J].
AHMED, EM ;
BASHIR, AK ;
ELKHEIR, YM .
PLANTA MEDICA, 1984, 50 (01) :74-77
[3]
Molluscicidal activity of some Saudi Arabian Euphorbiales against the snail Biomphalaria pfeifferi [J].
Al-Zanbagi, NA ;
Banaja, AEA ;
Barrett, J .
JOURNAL OF ETHNOPHARMACOLOGY, 2000, 70 (02) :119-125
[4]
A Blind Comparison of Simple Bench-top Bioassays and Human Tumour Cell Cytotoxicities as Antitumor Prescreens [J].
Anderson, J. E. ;
Goetz, C. M. ;
McLaughlin, J. L. ;
Suffness, M. .
PHYTOCHEMICAL ANALYSIS, 1991, 2 (03) :107-111
[5]
Baptista Darcilio F., 1994, Southeast Asian Journal of Tropical Medicine and Public Health, V25, P419
[6]
Bilia AR, 2000, PHYTOTHER RES, V14, P126, DOI 10.1002/(SICI)1099-1573(200003)14:2&lt
[7]
126::AID-PTR553&gt
[8]
3.0.CO
[9]
2-V
[10]
The global status of schistosomiasis and its control [J].
Chitsulo, L ;
Engels, D ;
Montresor, A ;
Savioli, L .
ACTA TROPICA, 2000, 77 (01) :41-51