Elasticity reconstruction from experimental MR displacement data: initial experience with an overlapping subzone finite element inversion process

被引:60
作者
Van Houten, EEW [3 ]
Weaver, JB
Miga, MI
Kennedy, FE
Paulsen, KD
机构
[1] Dartmouth Hitchcock Med Ctr, Dept Radiol, Lebanon, NH 03766 USA
[2] Norris Cotton Canc Ctr, Lebanon, NH 03766 USA
[3] Dartmouth Coll, Thayer Sch Engn, Hanover, NH 03755 USA
关键词
MR elastography; experimental elasticity reconstruction; viscoelastic tissue behavior; finite element inversion techniques;
D O I
10.1118/1.598861
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
The determination of the elastic property distribution in heterogeneous gel samples with a finite element based reconstruction scheme is considered. The algorithm operates on small overlapping subzones of the total field to allow for a high degree of spatial discretization while maintaining computational tractability. By including a Maxwellian-type viscoelastic property in the model physics and optimizing the spatial distribution of this property in the same manner as elasticity, a Young's modulus image is obtained which reasonably reflects the true distribution within the gel. However, the image lacks the clarity and accuracy expected based on simulation experience. Preliminary investigations suggest that transient effects in the data are the cause of a significant mismatch between the inversion model, which assumes steady-state conditions, and the actual displacements as measured by a phase contrast MR technique. (C) 2000 American Association of Physicists in medicine.
引用
收藏
页码:101 / 107
页数:7
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