Emerging roles of β-arrestins

被引：32

作者：

Buchanan, F. Gregory

DuBois, Raymond N.

机构：

[1] Vanderbilt Ingram Canc Ctr, Nashville, TN 37232 USA

[2] Vanderbilt Univ, Med Ctr, Nashville, TN USA

来源：

CELL CYCLE | 2006年 / 5卷 / 18期

关键词：

B-arrestin; arrestin; development; migration; metastasis; nuclear; review; EGFR; Src; Wnt;

D O I：

10.4161/cc.5.18.3212

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Arrestins were originally characterized as structural adaptor proteins which modulate the desensitization and trafficking of seven-membrane-spanning receptors. From these seminal observations a multitude of novel functions for this gene family have arisen. Here we review the recently identified roles for beta-arrestin including its nuclear function and roles in development, cellular migration, and metastasis.

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页码：2060 / 2063

页数：4

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