Recovery after damage to motor cortical areas

被引:169
作者
Nudo, RJ [1 ]
机构
[1] Univ Kansas, Med Ctr, Ctr Aging, Kansas City, KS 66160 USA
关键词
D O I
10.1016/S0959-4388(99)00027-6
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Until recently, the neural bases underlying recovery of function after damage to the cerebral cortex were largely unknown. Recent results from neuroanatomical and neurophysiological studies in animal models have demonstrated that after cortical damage, long-term and widespread structural and functional alterations take place in the spared cortical tissue. These presumably adaptive changes may play an important role in functional recovery.
引用
收藏
页码:740 / 747
页数:8
相关论文
共 73 条
[1]   Electrophysiological transcortical diaschisis after cortical photothrombosis in rat brain [J].
BuchkremerRatzmann, I ;
August, M ;
Hagemann, G ;
Witte, OW .
STROKE, 1996, 27 (06) :1105-1109
[2]   Extended brain disinhibition following small photothrombotic lesions in rat frontal cortex [J].
BuchkremerRatzmann, I ;
Witte, OW .
NEUROREPORT, 1997, 8 (02) :519-522
[3]   FUNCTIONAL RECOVERY OF FORELIMB RESPONSE CAPACITY AFTER FORELIMB PRIMARY MOTOR CORTEX DAMAGE IN THE RAT IS DUE TO THE REORGANIZATION OF ADJACENT AREAS OF CORTEX [J].
CASTROALAMANCOS, MA ;
BORRELL, J .
NEUROSCIENCE, 1995, 68 (03) :793-805
[4]   A functional MRI study of subjects recovered from hemiparetic stroke [J].
Cramer, SC ;
Nelles, G ;
Benson, RR ;
Kaplan, JD ;
Parker, RA ;
Kwong, KK ;
Kennedy, DN ;
Finklestein, SP ;
Rosen, BR .
STROKE, 1997, 28 (12) :2518-2527
[5]  
Duncan P.W., 1997, TOPSTROKE REHABIL, V4, P51, DOI DOI 10.1310/KYD7-HN2K-VGYG-8C98
[6]  
FEENEY DM, 1987, CRIT REV NEUROBIOL, V3, P135
[7]  
Finklestein SP, 1996, ADV NEUROL, V71, P413
[8]  
FISEDAL A, 1999, J CEREB BLOOD FLOW M, V19, P997
[9]   Recovery of motor function after focal cortical injury in primates: compensatory movement patterns used during rehabilitative training [J].
Friel, KM ;
Nudo, RJ .
SOMATOSENSORY AND MOTOR RESEARCH, 1998, 15 (03) :173-189
[10]  
GOLDSTEIN L, 1996, NEUROSURGERY, P459