Triterpenes from Tripterygium wilfordii Hook

被引：49

作者：

Yang, J. -H.

Luo, S. -D.

Wang, Y-S.

Zhao, J. -F.

Zhang, H. -B.

Li, L. ^{[1
]}

机构：

[1] Yunnan Univ, Ctr Adv Studies Med & Organ Chem, Sch Pharm, Kunming 650091, Yunnan, Peoples R China

[2] Chinese Acad Sci, Grad Sch, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources, Kunming 650204, Yunnan, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2006年 / 8卷 / 05期

关键词：

Tripterygium wilfordii Hook.f; celastraceae; triterpenes; tripterfrielanons A-B;

D O I：

10.1080/10286020500172665

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Two new friedelane-type triterpenes, tripterfrielanons A (1) and B (2), along with six known triterpenoids, friedelin (3), canophyllal (4), canophyltalic acid (5), 3-oxo-29-hydroxyfriedelane (6), wilforlide A (7), wilforlide B (8), have been isolated from the EtOH extract of the roots of Tripterygitan wilfordii Hook.f. Compounds 4, 5, 6 were isolated for the first time from this plant. The new triterpenes 1 and 2 exhibited mild cytotoxic activity against human Hela cell lines in vitro. The assay showed the IC50 of 1 and 2 were 8.5 and 25 mu g/mL, respectively.

引用

页码：425 / 429

页数：5

共 8 条

[1]

Terpenoids of Syzygium formosanum [J].