Six- versus five-membered ring formation in radical cyclization of 1-vinyl-5-methyl-5-hexenyl radicals

被引：22

作者：

Gómez, AM ^{[1
]}

Company, MD ^{[1
]}

Uriel, C ^{[1
]}

Valverde, S ^{[1
]}

López, JC ^{[1
]}

机构：

[1] CSIC, Inst Quim Organ Gen, E-28006 Madrid, Spain

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 28期

关键词：

D O I：

10.1016/S0040-4039(02)00866-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Radical cyclization of 1-vinyl-5-methyl-5-hexenyl radicals (radical numbering) affords six-membered ring products prevailing over the isomeric five-membered ring compounds: the former are generated through two reaction pathways: 6-endo-trig ring closure and rearrangement of intermediate methylenecyclopentyl radicals obtained by 5-exo trig cyclization. (C) 2002 Elsevier Science Ltd. All rights reserved.

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页码：4997 / 5000

页数：4

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