Epistasis and hybrid sterility in Saccharomyces

被引：81

作者：

Greig, D

Borts, RH

Louis, EJ

Travisano, M

机构：

[1] UCL, Dept Biol, Galton Lab, London WC1E 6BT, England

[2] Univ Houston, Dept Biol & Biochem, Houston, TX 77204 USA

[3] Univ Leicester, Dept Genet, Leicester LE1 7RH, Leics, England

来源：

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES | 2002年 / 269卷 / 1496期

关键词：

speciation; tetraploid; meiosis; yeast; evolution;

D O I：

10.1098/rspb.2002.1989

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Hybrid sterility is thought to be due to deleterious epistatic interactions between genes from different species. Here we demonstrate that dominant genic incompatibility does not contribute to sterility in hybrids between Saccharomyces cerevisiae and five closely related species. Sterile diploids were made fertile by genome doubling to produce hybrid tetraploids. Based on these and previous results, we conclude that neither genic incompatibility nor classical chromosomal speciation models apply.

引用

页码：1167 / 1171

页数：5

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