Oxygen therapy and toxicity

被引：25

作者：

Manning, AM ^{[1
]}

机构：

[1] Angell Mem Anim Hosp, Boston, MA 02130 USA

来源：

VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE | 2002年 / 32卷 / 05期

关键词：

D O I：

10.1016/S0195-5616(02)00043-8

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Oxygen (O-2) supplementation increases the O-2 content of blood, increases the partial pressure of oxygen (PO2) in the capillary blood, and improves tissue delivery of O-2. In addition to improving tissue oxygenation, the administration of O-2 may improve the function of O-2-dependent cellular systems, such as the cytochrome P-450 system, which is important to drug and toxin metabolism; nitric oxide synthase, which regulates vasodilation; and host defense systems. Improved tissue oxygenation is also beneficial for wound healing. Given the important contributions that supplemental O-2 can make, it is no wonder that O-2 is one of the most common drugs administered in the emergency and intensive care settings.

引用

页码：1005 / +

页数：17

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