Regioselective synthesis of alkylpyrroles from imines and nitroalkenes by lanthanide compounds

被引：61

作者：

Shiraishi, H ^{[1
]}

Nishitani, T ^{[1
]}

Nishihara, T ^{[1
]}

Sakaguchi, S ^{[1
]}

Ishii, Y ^{[1
]}

机构：

[1] Kansai Univ, Res Ctr, Fac Engn & High Technol, Dept Appl Chem, Suita, Osaka 5648680, Japan

来源：

TETRAHEDRON | 1999年 / 55卷 / 49期

关键词：

pyrroles; imines; nitroalkenes; samarium compounds;

D O I：

10.1016/S0040-4020(99)00855-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various types of substituted alkylpyrroles were synthesized in regioselective manner by the cyclization of nitroalkenes with imines catalyzed by Sm(Oi-Pr)(3) under mild conditions. Tetrahydroindole derivative was also synthesized in fair yield by the use of cyclic nitroalkene and imine as starting material. This method provides a novel alternative route for the regioselective synthesis of substituted alkylpyrrole derivatives. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：13957 / 13964

页数：8

共 20 条

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