Dynamic Contrast-Enhanced MR Imaging of the Liver: Current Status and Future Directions

被引:74
作者
Do, Richard Kinh Gian [1 ]
Rusinek, Henry [1 ]
Taouli, Bachir [1 ]
机构
[1] NYU, Dept Radiol, Langone Med Ctr, MRI, New York, NY 10016 USA
关键词
Liver; MR imaging; Perfusion; Dynamic contrast enhancement; Fibrosis; Cirrhosis; Hepatocellular carcinoma; Metastases; ENDOTHELIAL GROWTH-FACTOR; HEPATIC PERFUSION PARAMETERS; HEPATOCELLULAR-CARCINOMA; PHARMACOKINETIC ANALYSIS; COLORECTAL-CANCER; TRACER KINETICS; PHASE-II; FIBROSIS; ANGIOGENESIS; FLOW;
D O I
10.1016/j.mric.2009.01.009
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
100231 [临床病理学]; 100902 [航空航天医学];
摘要
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MR imaging) is emerging as a tool that can quantify changes in liver perfusion that occur in both diffuse and focal liver diseases. Recent data show promise for DCE-MR imaging of the liver in diagnosing fibrosis and cirrhosis before morphologic changes can be detected. It may also be valuable in the assessment of hepatocellular carcinoma and liver metastases. Acquisition parameters, postprocessing methods, applications, and recent results of DCE-MR imaging of the liver are also described. Finally, it reviews the limitations and future directions of DCE-MR imaging for liver applications.
引用
收藏
页码:339 / +
页数:12
相关论文
共 57 条
[1]
Characterization of hepatocellular carcinoma and colorectal liver metastasis by means of perfusion MRI [J].
Abdullah, Siraj Saadaldin ;
Pialat, Jean Baptiste ;
Wiart, Marlene ;
Duboeuf, Francois ;
Mabrut, Jean-Yves ;
Bancel, Brigitte ;
Rode, Agnes ;
Ducerf, Christian ;
Baulieux, Jacques ;
Berthezene, Yves .
JOURNAL OF MAGNETIC RESONANCE IMAGING, 2008, 28 (02) :390-395
[2]
Phase II study of sorafenib in patients with advanced hepatocellular carcinoma [J].
Abou-Alfa, Ghassan K. ;
Schwartz, Lawrence ;
Ricci, Sergio ;
Amadori, Dino ;
Santoro, Armando ;
Figer, Arie ;
De Greve, Jacques ;
Douillard, Jean-Yves ;
Lathia, Chetan ;
Schwartz, Brian ;
Taylor, Ian ;
Moscovici, Marius ;
Saltz, Leonard B. .
JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (26) :4293-4300
[3]
Evaluation of liver fibrosis: A concise review [J].
Afdhal, NH ;
Nunes, D .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2004, 99 (06) :1160-1174
[4]
Chemotherapy for Colorectal Cancer Liver Metastases [J].
Alberts, Steven R. ;
Wagman, Lawrence D. .
ONCOLOGIST, 2008, 13 (10) :1063-1073
[5]
Hepatic flow parameters measured with MR imaging and Doppler US: Correlations with degree of cirrhosis and portal hypertension [J].
Annet, L ;
Materne, R ;
Danse, E ;
Jamart, J ;
Horsmans, Y ;
Van Beers, BE .
RADIOLOGY, 2003, 229 (02) :409-414
[6]
Single breath-hold T1 measurement using low flip angle TrueFISP [J].
Bokacheva, L ;
Huang, AJ ;
Chen, Q ;
Oesingmann, N ;
Storey, P ;
Rusinek, H ;
Lee, VS .
MAGNETIC RESONANCE IN MEDICINE, 2006, 55 (05) :1186-1190
[7]
Quantitative determination of Gd-DTPA concentration in T1-weighted MR renography studies [J].
Bokacheva, Louisa ;
Rusinek, Henry ;
Chen, Qun ;
Oesingmann, Niels ;
Prince, Chekema ;
Kaur, Manmeen ;
Kramer, Elissa ;
Lee, Vivian S. .
MAGNETIC RESONANCE IN MEDICINE, 2007, 57 (06) :1012-1018
[8]
MR MEASUREMENTS OF MESENTERIC VENOUS FLOW - PROSPECTIVE EVALUATION IN HEALTHY-VOLUNTEERS AND PATIENTS WITH SUSPECTED CHRONIC MESENTERIC ISCHEMIA [J].
BURKART, DJ ;
JOHNSON, CD ;
READING, CC ;
EHMAN, RL .
RADIOLOGY, 1995, 194 (03) :801-806
[9]
Gadobenate dimeglumine 0.5 M solution for injection (MultiHance®):: Pharmaceutical formulation and physicochemical properties of a new magnetic resonance imaging contrast medium [J].
de Haën, C ;
Cabrini, M ;
Akhnana, L ;
Ratti, D ;
Calabi, L ;
Gozzini, L .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1999, 23 :S161-S168
[10]
Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis [J].
El-Serag, Hashem B. ;
Rudolph, Lenhard .
GASTROENTEROLOGY, 2007, 132 (07) :2557-2576