A novel Linear Code® nomenclature for complex carbohydrates

被引:54
作者
Banin, E [1 ]
Neuberger, Y [1 ]
Altshuler, Y [1 ]
Halevi, A [1 ]
Inbar, O [1 ]
Nir, D [1 ]
Dukler, A [1 ]
机构
[1] Glycominds Ltd, IL-71291 Lod, Israel
关键词
Linear Code; glycomics; nomenclature; carbohydrates; glycobiology;
D O I
10.4052/tigg.14.127
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Linear Code is a new syntax for representing glycoconjugates and their associated molecules in a simple linear fashion. Similar to the straightforward single letter nomenclature of DNA and proteins., Linear Code presents glycoconjugates in a canonic, compact and practical form while accounting for all relevant stereochemical and structural configurations. It uses a single letter code to represent each monosaccharide and includes a condensed description of the connections between monosaccharides and their modifications, allowing a simple linear representation of these compounds. The new linear syntax enables the implementation of bioinformatics tools for investigation and analysis of glyco-molecules and their biology.
引用
收藏
页码:127 / 137
页数:11
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