Pathogenesis of dengue virus diseases: missing pieces in the jigsaw

被引：43

作者：

BielefeldtOhmann, H

机构：

[1] Centre for Molecular Biotechnology (Arbovirology Group), School of Life Science, Queensland University of Technology, Brisbane, QLD 4001

来源：

TRENDS IN MICROBIOLOGY | 1997年 / 5卷 / 10期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/S0966-842X(97)01126-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The mechanisms involved in the pathogenesis of dengue hemorrhagic fever and dengue shock syndrome remain unresolved. Antibody-dependent enhancement of infection has long been thought to play a central role; however, this remains unverified. The alternative hypothesis that virus variation, virulence and dynamics may account for severe dengue disease, particularly in children, should be considered.

引用

页码：409 / 413

页数：5

共 57 条

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