Biocompatible high-moment FeCo-Au magnetic nanoparticles for magnetic hyperthermia treatment optimization

被引:53
作者
Kline, Timothy L. [1 ]
Xu, Yun-Hao [1 ]
Jing, Ying [1 ]
Wang, Jian-Ping [1 ]
机构
[1] Univ Minnesota, Dept Elect & Comp Engn, Ctr Micromagnet & Informat Technol, Minneapolis, MN 55455 USA
基金
美国国家科学基金会;
关键词
Hyperthermia; Cancer treatment; Tumor cell; Magnetic fluid; Nanoparticles; Core-shell; Specific absorption rate; Physical vapor deposition; High-moment; Au shell; FIELD; PARTICLES; FLUIDS;
D O I
10.1016/j.jmmm.2009.02.079
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
A great deal of attention has been paid to the use of magnetite nanoparticles as heating elements in the research of magnetic fluid hyperthermia. However, these particles have a relatively low magnetization and as a result, have low heating efficiency as well as difficulties in detection applications. To maximize heating efficiency we propose and show the use of high-moment Fe(Co)-Au core-shell nanoparticles. Using a physical vapor nanoparticle-deposition technique the high-moment nanoparticles were synthesized. The water-soluble particles were placed in an AC magnetic field of variable magnetic field frequencies. The temperature rise was measured and compared to theory. (c) 2009 Published by Elsevier B.V.
引用
收藏
页码:1525 / 1528
页数:4
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