Turning Meiosis into Mitosis

被引：272

作者：

d'Erfurth, Isabelle ^{[1
]}

Jolivet, Sylvie ^{[1
]}

Froger, Nicole ^{[1
]}

Catrice, Olivier ^{[2
]}

Novatchkova, Maria ^{[3
]}

Mercier, Raphael ^{[1
]}

机构：

[1] INRA, UR254, IJPB, F-78026 Versailles, France

[2] CNRS, UPR2355, Gif Sur Yvette, France

[3] Res Inst Mol Pathol, A-1030 Vienna, Austria

来源：

PLOS BIOLOGY | 2009年 / 7卷 / 06期

关键词：

ARABIDOPSIS-THALIANA; GENE; APOMIXIS; PROGRESSION; RESOURCE; APC/C; LINES; EMI2;

D O I：

10.1371/journal.pbio.1000124

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Apomixis, or asexual clonal reproduction through seeds, is of immense interest due to its potential application in agriculture. One key element of apomixis is apomeiosis, a deregulation of meiosis that results in a mitotic-like division. We isolated and characterised a novel gene that is directly involved in controlling entry into the second meiotic division. By combining a mutation in this gene with two others that affect key meiotic processes, we created a genotype called MiMe in which meiosis is totally replaced by mitosis. The obtained plants produce functional diploid gametes that are genetically identical to their mother. The creation of the MiMe genotype and apomeiosis phenotype is an important step towards understanding and engineering apomixis.

引用

页数：10

共 32 条

[1] Confocal microscopy of whole ovules for analysis of reproductive development:: the elongate1 mutant affects meiosis II [J].