Peritoneal membrane failure in peritoneal dialysis patients

被引:21
作者
Krediet, RT [1 ]
van Esch, S [1 ]
Smit, W [1 ]
Michels, WM [1 ]
Zweers, MM [1 ]
Ho-dac-Pannekeet, MM [1 ]
Struijk, DG [1 ]
机构
[1] Univ Amsterdam, Acad Med Ctr, Dept Med, Div Nephrol, NL-1105 AZ Amsterdam, Netherlands
关键词
peritoneal dialysis; continuous ambulatory ultrafiltration failure; pathogenetic mechanisms;
D O I
10.1159/000065202
中图分类号
R5 [内科学];
学科分类号
1002 [临床医学]; 100201 [内科学];
摘要
A review is given of the conditions associated with peritoneal membrane failure, and the possible causes. Ultra-filtration failure is the most important manifestation. It is mostly associated with high transport rates of low molecular weight solutes suggesting the presence of a large vascular surface area. Enlargement of the peritoneal surface area can be functional (effective surface area: more perfused microvessels) or anatomic (more microvessels). The former is likely to be present in some patients in the beginning of peritoneal dialysis, and also during peritonitis. The latter can develop in long-term peritoneal dialysis. Copyright (C) 2002 S. Karger AG, Basel.
引用
收藏
页码:489 / 493
页数:5
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