Molecular mechanisms of neutrophil recruitment elicited by bacteria in the lungs

被引:146
作者
Mizgerd, JP [1 ]
机构
[1] Harvard Univ, Sch Publ Hlth, Physiol Program, Boston, MA 02115 USA
关键词
adhesion molecules; cytokines; innate immunity; NF-kappa B; pneumonia;
D O I
10.1006/smim.2001.0349
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The recruitment of leukocytes to an extravascular destination requires intercellular communication between tissue cells and leukocytes. The molecules mediating this intercellular communication play differing roles in recruiting different types of leukocytes, in response to different stimuli, in different tissues, and in different hosts. The present communication reviews the adhesion molecules, chemokines, other cytokines, and NF-kappaB proteins which regulate the recruitment Of neutrophils elicited by bacteria in the lungs.
引用
收藏
页码:123 / 132
页数:10
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