Nonalcoholic steatohepatitis

Nonalcoholic steatohepatitis (NASH) is an important form of chronic liver disease that has the appearance of alcoholic hepatitis on biopsy but occurs in the absence of alcohol use. it is a frequent cause of chronically elevated serum aminotransferase levels, but surgical studies and autopsy results suggest that it may not always be associated with biochemical evidence of chronic liver injury. NASH has been found to cause progressive liver fibrosis and ultimately cirrhosis and death in some patients. The diagnosis is established by liver biopsy in the proper clinical setting, and the mainstay of treatment is weight loss in those patients who are obese.