Spontaneous oscillation of oxy- and deoxy- hemoglobin changes with a phase difference throughout the occipital cortex of newborn infants observed using non-invasive optical topography

被引：113

作者：

Taga, G

Konishi, Y

Maki, A

Tachibana, T

Fujiwara, M

Koizumi, H

机构：

[1] Univ Tokyo, Dept Pure & Appl Sci, Meguro Ku, Tokyo 1538902, Japan

[2] Japan Sci & Technol Corp, PRESTO, Tokyo, Japan

[3] Saitama Med Sch, Dept Pediat, Moroyama, Saitama, Japan

[4] Hitachi Ltd, Cent Res Lab, Tokyo, Japan

[5] Hitachi Med Corp, Ultrasound Div, Chiba, Japan

[6] Hitachi Ltd, Adv Res Lab, Hatoyama, Saitama, Japan

来源：

NEUROSCIENCE LETTERS | 2000年 / 282卷 / 1-2期

关键词：

optical topography; near-infrared light spectroscopy; newborn; occipital cortex; oscillation; cerebral blood volume; nonlinear dynamics;

D O I：

10.1016/S0304-3940(00)00874-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We investigated spontaneous changes in the cerebral oxygenation state of infants during quiet sleeping by using a form of multi-channel near-infrared spectroscopy: non-invasive optical topography. Eight infants born at 32-39 weeks were studied at postconceptional term age (38-43 weeks). Spatially synchronized oscillations of changes in the concentration of oxy- and deoxy- hemoglobin ([oxy-Hb] and [deoxy-Hb]) were observed throughout the occipital cortex. Time series analysis based on the theory of non-linear oscillators showed that the mean periods of the oscillation for each infant ranged from 11 to 18 s. The phase lag of [oxy-Hb] relative to [deoxy-Hb] was stable at about 3 pi/4. This phase difference may result from interplay between the vasomotion and the oxygen consumption in relation to brain activity. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：101 / 104

页数：4

共 20 条

[1] CYCLICAL VARIATIONS IN CEREBRAL BLOOD-FLOW VELOCITY [J].