Cellware - a multi-algorithmic software for computational systems biology

被引：38

作者：

Dhar, P ^{[1
]}

Meng, TC ^{[1
]}

Somani, S ^{[1
]}

Ye, L ^{[1
]}

Sairam, A ^{[1
]}

Chitre, M ^{[1
]}

Hao, Z ^{[1
]}

Sakharkar, K ^{[1
]}

机构：

[1] Bioinformat Inst, Syst Biol Grp, Singapore 138671, Singapore

来源：

BIOINFORMATICS | 2004年 / 20卷 / 08期

关键词：

D O I：

10.1093/bioinformatics/bth067

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The intracellular environment of a cell hosts a wide variety of enzymatic reactions, diffusion events, molecular binding, polymerization and metabolic channeling. To transform these biological events into a computational framework, distinct modeling strategies are required. While currently no tool is capable of capturing all these events, progress is being made to create an integrated environment for the modeling community. To address this niche requirement, Cellware has been developed to offer a multi-algorithmic environment for modeling and simulating both deterministic and stochastic events in the cell.

引用

页码：1319 / 1321

页数：3

共 7 条

[1]

HUCKA M, 1983, BIOINFORMATICS, V19, P524

[2] STOCKS: STOChastic kinetic Simulations of biochemical systems with gillespie algorithm [J].

Kierzek, AM .

BIOINFORMATICS, 2002, 18 (03) :470-481

[3] STOCHSIM:: modelling of stochastic biomolecular processes [J].

Le Novère, N ;

Shimizu, TS .

BIOINFORMATICS, 2001, 17 (06) :575-576

[4] The Virtual Cell: a software environment for computational cell biology [J].

Loew, LM ;

Schaff, JC .

TRENDS IN BIOTECHNOLOGY, 2001, 19 (10) :401-406

[5]

MENDES P, 1993, COMPUT APPL BIOSCI, V9, P563

[6] E-CELL: software environment for whole-cell simulation [J].

Tomita, M ;

Hashimoto, K ;

Takahashi, K ;

Shimizu, TS ;

Matsuzaki, Y ;

Miyoshi, F ;

Saito, K ;

Tanida, S ;

Yugi, K ;

Venter, JC ;

Hutchison, CA .

BIOINFORMATICS, 1999, 15 (01) :72-84

[7] Modeling biological systems using Dynetica - a simulator of dynamic networks [J].

You, LC ;

Hoonlor, A ;

Yin, J .

BIOINFORMATICS, 2003, 19 (03) :435-436

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