Structure of sch 68631: A new hepatitis C virus proteinase inhibitor from Streptomyces sp

被引:38
作者
Chu, M
Mierzwa, R
Truumees, I
King, A
Patel, M
Berrie, R
Hart, A
Butkiewicz, N
DasMahapatra, B
Chan, TM
Puar, MS
机构
[1] Schering-Plough Research Institute, Keniworth, NJ 07003
关键词
D O I
10.1016/0040-4039(96)01626-7
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel hepatitis C virus (HCV) proteinase inhibitor, Sch 68631 (1), was isolated from the fermentation culture broth of Streptomyces sp. The structure of 1 was elucidated by analyses of spectroscopic data and shown to be a new member of the phenanthrenequinone family of compounds. Copyright (C) 1996 Elsevier Science Ltd
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页码:7229 / 7232
页数:4
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